We begin this program in the weight room, where Dr. Moran describes the physiologic and microanatomic events that helped a bodybuilder (who we later learn to be his son, Dave Jr.) add 50 pounds of solid skeletal muscle to his 200-pound frame. After describing the overall structure of the three classes of muscle — skeletal muscle, cardiac muscle, and smooth muscle — we go to the laboratory. Here, each category of muscle tissue is described in a fascinating, easy-to-learn manner. Dr. Moran — who has been called by his students “the David Attenborough of tissue and cell biology” — takes us on a pleasant, fascinating journey from simple to complex. First, each type of muscle is seen at low magnification on the light microscope, and then at higher magnifications. Finally, the structural details that have been seen with the light microscope are depicted by a striking series of low, intermediate, and high magnification transmission electron micrographs taken by Carter Rowley, one of the best electron microscopists in the field.
During this half-hour video program, Dr. Moran consistently emphasizes the intimate relationship between structure and function, which is nowhere better seen than in the remarkable macromolecular organization of muscle tissue.
The presentation is followed by a ten-minute “practical exam” on which students can test their new-found knowledge — or review their knowledge for bigger and better examinations to come.